It would be aspirin to have a positive effect on cancer patients, reducing inflammation and improving cellular repair processes, as well as counteracting the metastatic process. The confirmation of a very recent English study
Nowadays, given the prevalence of cancer-related deaths, especially in those undeveloped countries with little access to diagnostic and therapeutic options, a cancer therapy that is as accessible and affordable as possible is vital. For this reason and the fact that the development of new anti-cancer drugs is quite expensive, the exploration of existing approved drugs for the treatment of cancer is growing.
In this regard, it would seem that aspirin, or acetylsalicylic acid, an anti-inflammatory and analgesic drug commonly used in the treatment of pain and fever in various diseases, can actually prevent the spread of metastases and the onset of complications associated with various forms. of cancer.
This is confirmed by recent research conducted by the University of Cardiff and published in the journal Open Biologyaccording to which aspirin would have a positive effect on cancer patients, reducing inflammation and improving cellular repair processes, as well as counteracting the metastatic process.
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I study
Assuming that certain biological mechanisms regulated by aspirin also play a role in the initiation and growth of cancer, the study researchers used a systematic review of the literature to address three main aspects of the use of aspirin in cancer therapy. cancer.
First, they summarized the current findings on the biological mechanisms by which aspirin can regulate metastatic processes in cancer. Next, they looked at various clinical trials to understand the effect of aspirin on cancer metastasis and survival. Finally, the researchers addressed the known side effects of aspirin use, commenting on its safety aspects in cancer therapy.
The observed effects of aspirin on the biological mechanisms involved in cancer development and growth would give rise to the expectation that aspirin slows the progression of cancer and reduces mortality from the disease.
The study involved 861 patients with Lynch syndrome, a condition that affects about one in 200 people and causes a genetic problem with DNA repair, making them much more at risk of bowel and uterine cancers.
A group of 427 took aspirin continuously for two years, while 434 took a placebo, and they were all followed for 10 years. From the analyzes carried out it emerged that those treated with two aspirins per day (600 mg) had a 42.6% decrease in cancer risk.
However, the researchers highlighted the absence of specific studies exploring the effect of aspirin on a wide range of cancers. In fact, most of the evidence comes from meta-analyzes of observational studies of individuals with cancer, a quarter of whom were taking aspirin.
Overall, the study would indicate that aspirin’s role in regulating various metabolic pathways makes it a potentially valuable and viable anti-cancer treatment option. Nonetheless, more research is needed on the use of aspirin in the treatment of some of the rarer forms of cancer and comprehensive research on adverse effects before promoting the use of aspirin in cancer therapy.
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