Combining different Covid-19 vaccines. There is an opinion of EU agencies

The administration of the Covid-19 vector vaccine first and then the mRNA formulation gives a good immune response. This is the latest opinion of the European Medicines Agency (EMA) and the European Center for Disease Prevention and Control (ECDC).

“Currently known scientific studies show that vaccination against Covid-19 in a regimen in which the vectored vaccine is administered first and then a formulation based on mRNA technology is safe and gives a better immune response than a regimen in which only vectored vaccines are used” – write the European Medicines Agency (EMA) and the European Center for Disease Prevention and Control (ECDC) in a joint communication.

This vaccination schedule can be used both for the primary vaccination course and for the booster dose. The use of this vaccine delivery model could allow European countries more flexibility in their vaccination campaign and, in the event of a substance shortage, more quickly protect as many people as possible against Covid-19.w – underline EMA and ECDC.

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European institutions have collected data on various combinations of combining the two types of vaccines available in the European Union. It was emphasized that the vaccine administration regimens in which the mRNA-based preparation is first taken and then vectored or two mRNA vaccines are mixed together are less well studied than the model in which the vector vaccine is administered first, then the mRNA is administered later.

However, there is enough evidence to conclude that it is acceptable – when the availability situation so requires – the administration of two different mRNA vaccines – it is stated in the Communication. Added that injecting the mRNA vaccine first and then the vector preparation later seems less favorable than the opposite sequence.

“But we only have limited data on such a vaccination model for the time being,” the journal reads.

Two vector vaccines against Covid-19, manufactured by companies, have been approved for use across the European Union AstraZeneka and Johnson & Johnson, as well as the preparation produced by the companies Pfizer and BioNTech and the concern’s vaccine Modern. The latter two substances use mRNA technology.

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In the published communication, the European Medicines Agency (EMA) and the European Center for Disease Prevention and Control (ECDC) again urge all EU residents to adopt the full course of immunization against Covid-19 and to follow recommendations on booster vaccinations.

‘The EU is currently experiencing an increasing number of infections during the ongoing Covid-19 pandemic, as well as an increase in hospitalizations. Vaccination continues to prevent the serious illness or death of many millions of EU citizens, and data show that hospitalizations and deaths remain lowest in those Member States where vaccination coverage is the highest, ‘reads the EMA and ECDC statement.

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About Peter Wilson

In love with technology, with an eye towards smartphones, he does not disdain any activity linked to the Nerd world. TV series, movies, manga, anime, and comics (Marvel addicted) are the order of the day.

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